List of Publications


1. “Total Synthesis of Fusarochromanone: a Potent Anti-cancer Agent”, Adelmund, S.; Solis, F.; Nicolasvu, C.;

Sangsura, S.; Landry, G.; Railey, M.; Rachal, P.; Lutz, J.; Salvatore, B. A.; and Mahdavian, E.; Manuscript in

Progress “Tetrahedron Letters”.

2. “Use of In-silico Assays for ADMET and Target Profiling of Fusarochromanone, Wynne, M.; Williams-Hart, T.;

Salvatore, B.A.; Mahdavian, E.; Submitted to the journal of in-silico Pharmacology, http://www.in-silicopharmacology.com/imedia/7232241715840055_article.pdf.

3. “Fusarochromanone Induces G1 Cell Cycle Arrest and Apoptosis in COS7 and HEK293 Cells”, Ying, G.; Chen, X.;

Chang, C.; Singh, K.; Barzegar, M.; Mahdavian, E.; Salvatore, B. A.; Huang, S.; PLOS ONE, 10 (9): 11. PMID:

25384025, PMCID: PMC4226581, 2014.

4. “Biological Activities of Fusarochromanone: A Potent Anti-Cancer Agent”, Mahdavian, E.; Williams-Hart, T.;

Furmanski, B.; Kevil, C.; Gopi, K.; Yoon-Jee, K.; Salvatore, B. A.; Huang, S.; Clifford, J.; BMC Research Notes, 7,

601. PMID: 25187308, PMCID: PMC4168212, 2014.

5. “Caspase Dependent Signaling Underlies Glioblastoma Cell Death in Response to the Fungal Metabolite, Fusarochromanone”, Mahdavian, E.; Marshall, M.; Martin, P.; Cagle, P.; Salvatore, B. A.; Quick, Q; Int J Mol Med.

34(3): 880-5. PMID: 25016928, PMCID: PMC4121350, 2014.

6. “Mitochondrial Targeting of a-Tocopheryl Tuccinate Enhances Its Pro-apototic and Anti-cancer Efficacy” Turánek, J.; Wang, X.-F.; Knötigová1, P.; Dong, L.-F.; Koudelka, S.; Mahdavian, E.; Procházka1, L.; Sangsura, S.; Vacek,

A.; Salvatore, B. A.; Neuzil, J., Free Radic Biol Med, 50: 1546-55, PMID 21402148, 2011.

7. “Mitochondrial Targeting of Vitamin E Succinate Enhances Transmission of its Activity via Mitochondrial Complex II” Dong, L.; Adlam, V.; Tilly, D.; Prochazka L.; Mahdavian, E.; Salvatore, B.; Neuzil, J., Journal of Biological Chemistry, 286:3717, PMID 21059645, 2011.

8. “Liposomal formulation of vitamin E analogs as an efficient and selective anti-cancer treatment” Turánek, J.;

Wang, X.-F.; Knötigová1, P.; Dong, L.-F.; Koudelka, S.; Mahdavian, E.; Procházka1, L.; Sangsura, S.; Vacek, A.;

Salvatore, B. A.; Neuzil, J., Applied Toxicology and Pharmacology, 237, 2009.

9. “A Novel Synthesis of Tocopheryl Amines and Amides”, Mahdavian, E.; Sangsura, S.; Landry, G.; Eytina, J.;

Salvatore, B.A., Tetrahedron Letters, 50, 19-21, 2009.

10. “Vitamin E amides, a new class of vitamin E analogues with enhanced pro-apoptotic activity” Tomic-Vatic, A.; EyTina, J.; Chapman, J.; Mahdavian E.; Neuzil, J.; Salvatore. B.A., Int. J . Cancer, 117, 188-193, 2005.

11. “Catalytic Cysteine of Thymidylate Synthase is Activated Upon Substrate Binding “, Jason Phan, J.; Mahdavian, E.; Minor, W.; Berger, S.; Spencer, H.T.; Dunlap, R.B.; Lebioda, L.; Biochemistry, 39, 6969-6978, 2000.

12. “Kinetic Studies on Drug Resistant Variants of Escherichia coli Thymidylate Synthase: Functional Effects of Amino Acid Substitutions at Residue 4”. Mahdavian, E.; Spencer, H.T.; Dunlap, R.B; Archives of Biochemistry and Biophysics, 368: 257-264, 1999.

 

Papers Presented at Professional Meetings

1. Elahe Mahdavian, and Brian Salvatore, "Synthesis of Vitamin E Analogs as Potential Anti-Cancer Agents", Bio-Research Day sponsored by NLPI, Shreveport, LA, April 2005, Poster.

2. Elahe Mahdavian, Charles Thompson, and Brian Salvatore, "Fusarochromanone and Its New Analogs as Potential Anti-Cancer & Anti-Angiogenic Compounds", College of Sciences Annual Student Research Forum, LSUS, May 2005, Poster.

3. Brian Salvatore, Elahe Mahdavian, and Jirka Neuzil, "Synthesis and Studies of a New Class of Pro-Apoptotic Amide Analogs of Tocopheryl Esters", Society for Free Radical Research 14th Annual Meeting, Queensland, Australia, December 2005, Oral.

4. Elahe Mahdavian, and Brian Salvatore, "Fusarochromanone and its Amide Analogs as Potential Anti-Cancer and Anti-Angiogenic Agents", Annual LA-BRIN Symposium, Baton Rouge, February 2006, Poster.

5. Smink Sangsura, Elahe Mahdavian, and Brian Salvatore, "The Synthesis of New Functional Domain Analogs of a-Tocopherol Succinate" LSUS College of Sciences Undergraduate Research Forum, April 2006, Oral. Elahe Mahdavian, "Biological-Activity Assessments of Fusarochromanone and its Amide analogs", Experimental Therapeutic Group, Feist Weiller Cancer Center, Shreveport, LA, June 2006, Oral.

6. Elahe Mahdavian, John Clifford, and Brian Salvatore, "Novel Derivatives of Fusarochromanone: Potential Therapeutic Compounds", American Association of Cancer Research (AACR) Annual Meeting, Los Angeles, CA, April 2007, Poster.

7. Elahe Mahdavian, Brian Salvatore, and John Clifford, "Development of Novel Anti-Cancer Agents Based on Fusarochromanone: LSUS COS Symposium, Shreveport, LA, April 2009, Oral.

8. Elahe Mahdavian, Bonnie Buckley, Mattew Sermons, John Clifford, and Brian Salvatore, "Development of Novel Anti-Cancer Agents: Regional IDeA Meeting, Charleston, SC, October 2009, Oral.

9. Elahe Mahdavian, John Clifford, and Brian Salvatore, "Development of Novel Anti-Cancer Agents Based on Fusarochromanone: LBRN Work in Progress, Shreveport, LA, December 2009, Oral.

10. Elahe Mahdavian, Bonnie Buckley, Matthew Sermons, “Development of Novel Anti-Cancer Agents”, LBRN Annual Symposium Baton Rouge, LA, January 2010, Oral.

11. Elahe Mahdavian, “Development of Novel Anti-Cancer Agents Based on Fusarochromanone”, Bioinformatics Affinity Group (BAG) Seminar Series LSUS, Shreveport, LA, February 2010, Oral.

12. Elahe Mahdavian, Bonnie Buckley, “Biosynthesis of Fusarochromanone”, LSUS College of Science Research Forum LSUS, Shreveport, LA, April 2010, Oral.

13. Elahe Mahdavian, Bonnie Buckley, John Clifford, Brian Salvatore, "Anti-Cancer Agents Based on Fusarochromanone: AACR Annual Meeting, Washington, DC, April 2010, Poster.

14. Elahe Mahdavian, Dakota Boston, Reid Grimes, “Development of Novel anti-Cancer Agents Based on Fusarochromanone”, LBRN Work In Progress, LSU-Shreveport, Shreveport, LA, September 2010, Oral.

19. Elahe Mahdavian “Development of Novel anti-Cancer Agents Based on Fusarochromanone”, Barlow Symposium, Feist Weiller Cancer Center, Shreveport, LA, September 2010, Poster.

20. Elahe Mahdavian and Brian Salvatore. “Novel Chemical Synthesis of Natural Product, Fusarochromanone”, AACR-ACS Joint Meeting on Chemistry in Cancer Research Meeting. San Diego, CA, January 2011, Poster.

21. Elahe Mahdavian, Dakota Boston, and Reid Grimes, Tara Williams-Hart, Brian Furmanski, John Clifford, Brian Salvatore. “Development of Novel Anti-Cancer Agents based on Fusarochromanone”. AACR 102nd Annual Meeting. Orlando, FL, April 2011, Poster.

22. Elahe Mahdavian, Tara Williams-Hart, Brian Furmanski, Christopher Kevil, John Clifford, and Brian Salvatore,

“Evaluation of Fusarochromanone: A Potent Inhibitor of Angiogenesis and Tumorigenesis”, IDeA meeting, Baton Rouge, LA, September 2011, Poster.

23. Vincent Goodinich, Emily Felty, Brian Salvatore, and Elahe Mahdavian, Chemical Synthesis of Novel Structural Analogs of Fusarochromanone”, IDeA meeting, Baton Rouge, LA, September 2011, Poster.

24. Mahreen, Ahmad; Salvatore, Brian; Mahdavian, Elahe. "In-vitro Cellular Assay to Determine Anti-Cancer Activity of Synthetic Fusarochromanone (FC101) and Analogs." LSUS College of Science Student Research Symposium. Shreveport, LA, April 2012, Oral.

25. Madison Wynne, Brian Salvatore, and Elahe Mahdavian. "Use of In-Silico Molecular Modeling Techniques in the Discovery of Fusarochromanone Induced Apoptotic Pathway." LSUS College of Science Student Research Symposium. Shreveport, LA, May 2013, Poster.

26. Elahe Mahdavian, “Evaluation of Fusarochromanone: A Potent Inhibitor of Angiogenesis and Tumorigenesis”, LBRN Work in Progress, LSUS, Shreveport, LA, November 2013, Oral.

27. Steven Adelmund. "Identifying the Biological Targets of Fusarochromanone Through Photoaffinity Labeling" 2014 LBRN Annual Meetting. New Orleans, LA, February 2014, Oral.

28. Elahe Mahdavian, “Evaluation of Fusarochromanone: A Potent Inhibitor of Angiogenesis and Tumorigenesis”, 12th Annual LBRN Meeting, Baton Rouge, LA, February 2014, Oral.